Condition: Homocystinuria · Sponsor: Travere Therapeutics, Inc.
The purpose of this study is to measure efficacy and safety of pegtibatinase treatment compared with placebo in participants with classical HCU receiving standard of care. Study details include: * Total Study duration: up to 38 weeks * Screening: * Initial Screening duration: up to 4 weeks * Pre-treatment Diet Standardization Period duration: up to 6 weeks * Blinded Treatment Duration: 24 weeks * 2-week blinded dose titration period * 22-week blinded assessment period * Safety Follow-Up: 4 weeks after last dose (as applicable for those not enrolling in the long term extension study, ENSEMBLE)
This description comes directly from the study's public registry record.
Travere Call Center · 1-877-659-5518 · medinfo@travere.com
Always discuss trial participation with your own doctor first.
| Phoenix Children's Hospital | Phoenix, Arizona, United States | Not Yet Recruiting |
| Yale University School of Medicine | New Haven, Connecticut, United States | Recruiting |
| Emory University | Atlanta, Georgia, United States | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago, Illinois, United States | Not Yet Recruiting |
| Maine Health - Maine Medical Center | Portland, Maine, United States | Recruiting |
| Uncommon Cures | Chevy Chase, Maryland, United States | Recruiting |
| The Mount Sinai Hospital | New York, New York, United States | Recruiting |
| Science 37 - Virtual Site | Morrisville, North Carolina, United States | Recruiting |
| Oregon Health and Science University | Portland, Oregon, United States | Not Yet Recruiting |
| Children's Hospital of Philadelphia | Philadelphia, Pennsylvania, United States | Recruiting |
| University of Pittsburgh Medical Center - Children's Hospital of Pittsburgh | Pittsburgh, Pennsylvania, United States | Recruiting |
| University of Texas Southwestern Medical Center | Dallas, Texas, United States | Recruiting |
+ 40 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06247085