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Study identifier: NCT06246799 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

Condition: Type 2 Diabetes (Adult Onset)  ·  Sponsor: The University of Texas Health Science Center at San Antonio

PhasePhase 3
Planned participants256
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The primary purpose of this study is to evaluate the efficacy, durability, and mechanism of HbA1c reduction produced by the combination of pioglitazone plus tirzepatide compared to metformin plus sitagliptin in patients with recently diagnosed type 2 diabetes mellitus.

This description comes directly from the study's public registry record.

Talk to the study team

Muhammad Abdul-Ghani, MD  ·  210-567-6691  ·  abdulghani@uthscsa.edu

Gozde Baskoy, PhD  ·  210-358-7200  ·  baskoy@uthscsa.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University Health System Texas Diabetic InstituteSan Antonio, Texas, United StatesRecruiting
UT Health Science CenterSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06246799