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Study identifier: NCT06246149 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Adjuvant Tebentafusp in High Risk Ocular Melanoma

Condition: Uveal Melanoma  ·  Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

PhasePhase 3
Planned participants290
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

At least 50% of patients with high-risk primary uveal melanoma will develop a recurrence following treatment of the primary tumour. Observation is currently the standard of care in the non-metastatic setting. Tebentafusp is the first agent proven to improve overall survival in patients with metastatic uveal melanoma in a randomized trial. Based on the results in the advanced setting, it is hypothesized that treatment with tebentafusp may reduce the risk of development of disease recurrence.

This description comes directly from the study's public registry record.

Talk to the study team

EORTC HQ  ·  +32 2 774 16 11  ·  eortc@eortc.org

Always discuss trial participation with your own doctor first.

Locations (15)

Northwell Health -Center for Advanced MedicineLake Success, New York, United StatesRecruiting
Cliniques Universitaires Saint-LucBrussels, BelgiumRecruiting
Centre Antoine LacassagneNice, FranceRecruiting
Institut Curie - Hôpital de ParisParis, FranceRecruiting
Charite - Universitaetsmedizin Berlin - Campus Benjamin FranklinBerlin, GermanyRecruiting
Universitaets Krankenhaus Eppendorf - Universitaetsklinikum Hamburg-Eppendorf KE - University Cancer CenterHamburg, GermanyRecruiting
Universitaetsklinikum Heidelberg - Frauenklinik / HautklinikHeidelberg, GermanyRecruiting
Leiden University Medical CentreLeiden, NetherlandsRecruiting
Erasmus MCRotterdam, NetherlandsRecruiting
Maria Sklodowska-Curie Memorial Cancer Centre - Maria Sklodowska-Curie National Research Institute of OncologyWarsaw, PolandRecruiting
Institut Catala d'Oncologia - ICO L'Hospitalet - Hospital Duran i Reynals (Institut Catala D'Oncologia)L'Hospitalet de Llobregat, SpainRecruiting
Hospital Clinico Universitario De ValladolidValladolid, SpainRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06246149