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Study identifier: NCT06244511 Synced from ClinicalTrials.gov · July 29, 2026
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Bipedal vs. Unipedal Exercises in Chronic Ankle Instability

Condition: Instability; Ankle (Ligaments) (Old Injury)  ·  Sponsor: Istanbul University - Cerrahpasa

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersNo

About this study

Ankle sprain is a commonly encountered condition in clinical practice, constituting approximately 15-30% of all musculoskeletal injuries. Long-term studies have demonstrated that up to 73% of patients experience at least one more ankle sprain following an acute ankle sprain. Inadequate treatment of acute ankle instability can lead to chronic ankle instability (CAI) in 30-70% of cases. Treatment approaches for CAI are classified into conservative and surgical methods. Typically, conservative treatment is initially employed to address proprioceptive deficits and static impairments. Passive, unidirectional treatments such as injections, electrotherapy, and ice, which do not target muscle strength, kinetic chain, tendon capacity, and cortical control, are reported to be insufficient or ineffective in treating CAI, relying solely on symptomatic relief. Therefore, therapeutic exercises are fundamental in CAI treatment, leading to positive developments in parameters such as strength, dynamic balance, functional status, quality of life, and injury risk. Among the most commonly used exercise approaches are proprioceptive and resistive exercises. Upon reviewing the literature, it is observed that bipedal exercises have been employed from the early stages of CAI. However, due to clinical symptoms such as pain, insecurity, and fear associated with loading the affected limb, patients tend to avoid putting weight on the affected limb, resulting in the frequent use of bipedal exercises in…

This description comes directly from the study's public registry record.

Talk to the study team

Ayşenur Erekdağ, MSc  ·  05548959013  ·  aysenurerekdag@gmail.com

Sezen Karabörklü Argut, PhD  ·  05301712421  ·  sezenpt@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Acibadem Mehmet Ali Aydinlar UniversityIstanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT06244511