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Study identifier: NCT06241599 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)

Condition: Recurrent or Metastatic Nasopharyngeal Carcinoma  ·  Sponsor: Sun Yat-sen University

PhasePhase 2/Phase 3
Planned participants300
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

To compare whether AK104 combined with GP or PFLL can improve survival benefit, safety and tolerability in nasopharyngeal carcinoma patients who have failed first-line treatment; To compare the survival benefits of GP or GFLL treatment in nasopharyngeal carcinoma patients who had failed first-line therapy; To compare the survival benefits of GP or GFLL combined with AK104 in patients with nasopharyngeal carcinoma who had failed first-line therapy.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

Department of Radiation Oncology, Sun Yat-Sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06241599