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Study identifier: NCT06235216 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Sacituzumab govitEcan in THYroid Cancers

Condition: Differentiated Thyroid Cancer · Anaplastic Thyroid Cancer  ·  Sponsor: Grupo Espanol de Tumores Neuroendocrinos

PhasePhase 2
Planned participants42
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

SETHY is a prospective, multicohort, phase II, single-arm, non-randomized, non-blinded, investigator-initiated study of sacituzumab govitecan in patients with advanced or metastatic radioactive-iodine refractory differentiated thyroid carcinoma (DTC) or anaplastic thyroid carcinoma (ATC). The main hypothesis is that treatment with sacituzumab govitecan, a anti-Trophoblast cell surface antigen 2 (TROP-2), could be an effective treatment option for patients with either differentiated and anaplastic thyroid neoplasms because TROP-2 is highly expressed at the membrane of DTC and ATC.

This description comes directly from the study's public registry record.

Talk to the study team

A responsible person Designated by the Sponsor  ·  +34 93 434 44 12  ·  investigacion@mfar.net

Always discuss trial participation with your own doctor first.

Locations (11)

Hospital Universitari Vall d'HebronBarcelona, SpainRecruiting
Complexo Hospitalario Universitario de FerrolFerrol, SpainNot Yet Recruiting
Institut Catala d´Oncologia (ICO) -HospitaletHospitalet de Llobregat (Barcelona), SpainRecruiting
Hospital Clínico San CarlosMadrid, SpainRecruiting
Hospital Universitario la PazMadrid, SpainRecruiting
Hospital Universitario Ramón y CajalMadrid, SpainNot Yet Recruiting
MD Anderson Cancer Center MadridMadrid, SpainRecruiting
Hospital General Universitario Morales MeseguerMurcia, SpainRecruiting
Hospital Universitario Central de AsturiasOviedo, SpainRecruiting
H.U. Marqués de ValdecillaSantander, SpainRecruiting
Hospital Universitario Miguel ServetZaragoza, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06235216