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Study identifier: NCT06228456 Synced from ClinicalTrials.gov · July 29, 2026
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Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention

Condition: Coronary Artery Disease  ·  Sponsor: University of Florida

PhasePhase 4
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The proposed study aims to assess the antiplatelet effects of more potent oral P2Y12 inhibition with low-dose ticagrelor (60 mg bid) compared with standard of care clopidogrel in patients with a high ABCD-GENE score (≥10). We hypothesize that ticagrelor is associated with better pharmacodynamic effects (i.e., lower platelet reactivity and high platelet reactivity rates) compared with clopidogrel in stable coronary artery disease patients undergoing percutaneous coronary intervention with a high ABCD-GENE score.

This description comes directly from the study's public registry record.

Talk to the study team

Francesco Franchi, MD  ·  9042442060  ·  francesco.franchi@jax.ufl.edu

Andrea Burton, MPH, CPH  ·  9042445617  ·  andrea.burton@jax.ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Florida JacksonvilleJacksonville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06228456