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Study identifier: NCT06227338 Synced from ClinicalTrials.gov · July 29, 2026
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ICG-fluorescence Imaging for Intraoperative Breast Cancer Margins Evaluation: a Dose-timing Study

Condition: Breast Cancer  ·  Sponsor: Jules Bordet Institute

PhaseNA
Planned participants250
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Designed in five-arm, single-center, prospective randomized, observational- interventional, open-label study which will evaluate patients with histological proven early-stage BC that will undergo planned BCS for their local treatment. Two preoperatively times frames will be used for the administration of a total of 5 different indocyanine green (ICG) dose as a single dose-patient arm. In the first time frame (intraoperative arms), the dose of, respectively 0.125 mg/kg and 0.25 mg/kg of ICG will be administered at induction anesthesia (at least 20 minutes before the BCS) in two subgroups. In the second time frame, (preoperative arms), the dose of, respectively, 0.5 mg/kg, 1 mg/kg, and 2 mg/kg of ICG will be administered 24 h before surgery in 3 subgroups.

This description comes directly from the study's public registry record.

Talk to the study team

Florin Pop, MD  ·  +322541  ·  catalin.florin.pop@hubruxelles.be

Always discuss trial participation with your own doctor first.

Locations (1)

Jules Bordet InstituteBrussels, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT06227338