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Study identifier: NCT06226155 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

Condition: HIV Infections · Pregnancy Related · Depression, Anxiety  ·  Sponsor: Massachusetts General Hospital

PhaseNA
Planned participants132
Who can joinAll sexes, 15 Years to 55 Years
Healthy volunteersNo

About this study

The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV treatment adherence among people living with HIV in Zimbabwe. The new intervention, TENDAI4PrEP, will be designed to improve PrEP uptake and persistence among pregnant persons in Zimbabwe. If feasibility, acceptability, and preliminary efficacy are demonstrated, the intervention will be ready for large-scale effectiveness/implementation testing. This program will has the potential to address a critical public health challenge impacting pregnant and postpartum persons in Zimbabwe: the prevention of HIV acquisition and transmission.

This description comes directly from the study's public registry record.

Talk to the study team

Conall O'Cleirigh  ·  617-643-0385  ·  cocleirigh@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of ZimbabweHarare, ZimbabweRecruiting

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Source record: clinicaltrials.gov/study/NCT06226155