Condition: Major Non-cardiac Surgery · Sponsor: Seoul National University Hospital
Study objective: To compare the effect of different perioperative blood pressure management strategies on major postoperative adverse outcomes / Study design: a multicenter, randomized controlled trial / Participants: 1896 patients undergoing major non-cardiac surgery / Methods: Patients are randomized into two groups, the individualized strategy (maintaining perioperative mean arterial pressure and systolic blood pressure more than -20% of their baseline values) or the conventional strategy (maintaining perioperative mean arterial pressure ≥65 mmHg and systolic blood pressure ≥90 mmHg in all patients). Then, the frequency of major postoperative adverse outcomes occurring within 7 postoperative days or before discharge (whichever occurs first). / Primary outcome: a composite of all-cause death, stroke, myocardial infarction, new or worsening congestive heart failure, unplanned coronary revascularization, and acute kidney injury, occuring within 7 postoperative days or before discharge (whichever occurs first).
This description comes directly from the study's public registry record.
Karam Nam, M.D., Ph.D. · 82-2-2072-0643 · karamnam@gmail.com
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| Seoul National University Bundang Hospital | Seongnam, South Korea | Recruiting |
| Seoul National University Hospital | Seoul, South Korea | Recruiting |
| Korea University Guro Hospital | Seoul, South Korea | Recruiting |
| Samsung Medical Center | Seoul, South Korea | Recruiting |
| Ajou University Hospital | Suwon, South Korea | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06225453