Condition: Colorectal Adenocarcinoma · Sponsor: Jonsson Comprehensive Cancer Center
This phase I trial tests whether fluoxetine (prozac) works to modify the tumor immune cells before surgery in patients with colorectal cancer. Fluoxetine is a commonly used selective serotonin reuptake inhibitor (SSRI) prescribed for major depressive disorder and generalized anxiety. Giving fluoxetine may modify the immune cell composition in the tumor and its microenvironment and may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread in patients with colorectal cancer.
This description comes directly from the study's public registry record.
Jasmine Mitchell, MD · 310-825-0712 · jlmitchell@mednet.ucla.edu
Always discuss trial participation with your own doctor first.
| UCLA / Jonsson Comprehensive Cancer Center | Los Angeles, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06225011