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Study identifier: NCT06224816 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Trial for the Evaluation of Customized 3D Printed NIV Nasal Masks in Premature Infants

Condition: Premature Lungs  ·  Sponsor: Hospital Universitario 12 de Octubre

PhaseNA
Planned participants60
Who can joinAll sexes, 0 Days to 30 Days
Healthy volunteersNo

About this study

Clinical trial with crossed groups, open, masked for the evaluation of the main outcome. Inclusion of all premature infants with a birth weight less than 1500 g requiring Non-invasive Ventilation (NIV). Premature will be randomised to start alternatively with MT or 3DM. Each patient included will be their own control at the same time, receiving each of the different mask models every 4 hours alternately. The study period will be a maximum of 7 days. To compare the time in which preterm maintain SatO2 below 85% with the 3DM versus the traditional mask (TM) in preterm \< 1500 g. Other secondary objectives regarding ventilation enhancement will be assessed, such as the number of bradycardias, cardiorespiratory arrest and need for resuscitation in the context of apnea. Also, skin lesions of the nose resulting from the pressure applied by any of the masks (TM or 3DM) and the need for analgesia and/or sedation for pain control or discomfort will be assessed. Parental perception and satisfaction will be assessed.

This description comes directly from the study's public registry record.

Talk to the study team

María Teresa Moral Pumarega  ·  649921733  ·  mmoralp@salud.madrid.org

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Universitario 12 de OctubreMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06224816