Condition: Constipation - Functional · Refractory Constipation · Fluoxetine · Sponsor: Xijing Hospital of Digestive Diseases
The goal of this observational study is to identify the characteristics of brain functional connectivity in refractory constipation and fluoxetine-sensitive patients. The main questions it aims to answer are: * Investigating the alterations in brain functional connectivity in patients with refractory constipation and fluoxetine-sensitive patients * Assessing the predictive value of brain functional connectivity regarding the efficacy of fluoxetine and standard protocol treatments for constipation. Participants will receive: * Standard physiological and psychological assessments of constipation * BOLD-fMRI tests * Standard protocol and fluoxetine treatment If there is a comparison group: Researchers will compare: Refractory group/Fluoxetine sensitive group to see the specific brain alterations.
This description comes directly from the study's public registry record.
Zhifeng Zhao · 13519171072 · zhaozhifeng@outlook.com
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| People's Hospital of Ningxia Hui Autonomous Region | Yinchuan, Ningxia, China | Recruiting |
| Xi'an International Medical Center Hospital | Xi'an, Shaanxi, China | Recruiting |
| Xijing Hospital, Fourth Military Medical University | Xi'an, Shaanxi, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06221722