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Study identifier: NCT06221683 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML

Condition: AML, Childhood · Acute Myeloid Leukemia  ·  Sponsor: Children's Hospital of Soochow University

PhasePhase 2
Planned participants500
Who can joinAll sexes, N/A to 18 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to estimate the rate (probability) of complete remission or complete remission with incomplete count recovery (CR/CRi) with negative MRD after induction I and II, event-free survival (EFS), and cumulative incidence (probability) of relapse (CIR), in patients receiving molecular/precision medicine and MRD-driven remission inductions, and to assess secondarily if there is an improvement over the AML2018 protocol.

This description comes directly from the study's public registry record.

Talk to the study team

Shaoyan Hu, MD, PhD  ·  +86-13771870462  ·  hsy139@126.com

Li Gao, MD  ·  +86-15821963190  ·  joygaoli@163.com

Always discuss trial participation with your own doctor first.

Locations (13)

First Affiliated Hospital Of University of Science and Technology of ChinaHefei, Anhui, ChinaNot Yet Recruiting
The Second Hospital of Anhui Medical UniversityHefei, Anhui, ChinaNot Yet Recruiting
Guangzhou Women and Children Medical CenterGuangzhou, Guangdong, ChinaNot Yet Recruiting
The First Affiliated Hospital of Guangxi Medical UniversityNanning, Guangxi, ChinaNot Yet Recruiting
Kaifeng Children's HospitalKaifeng, Henan, ChinaNot Yet Recruiting
The First Affiliated Hospital of Zhengzhou UniversityZhengzhou, Henan, ChinaNot Yet Recruiting
Third Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaNot Yet Recruiting
XiangYa Hospital Central South UniversityChangsha, Hunan, ChinaNot Yet Recruiting
Children's Hospital of Soochow UniversitySuzhou, Jiangsu, ChinaRecruiting
Xuzhou Children's HospitalXuzhou, Jiangsu, ChinaNot Yet Recruiting
Qilu Hospital of Shandong UniversityJinan, Shandong, ChinaNot Yet Recruiting
Children's Hospital Of Fudan UniversityShanghai, Shanghai Municipality, ChinaNot Yet Recruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06221683