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Study identifier: NCT06218914 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

Condition: Non-small Cell Lung Cancer · Colorectal Carcinoma · Pancreatic Ductal Adenocarcinoma  ·  Sponsor: AstraZeneca

PhasePhase 1
Planned participants108
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Phase I Study, a master protocol to investigate TCR-Engineered T cells recognizing KRAS mutations in adult subjects with Unresectable, Advanced, and/or Metastatic Solid Tumors.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (18)

Research SiteDuarte, California, United StatesRecruiting
Research SiteLos Angeles, California, United StatesRecruiting
Research SiteNewport Beach, California, United StatesRecruiting
Research SiteJacksonville, Florida, United StatesRecruiting
Research SiteChicago, Illinois, United StatesRecruiting
Research SiteWestwood, Kansas, United StatesRecruiting
Research SiteBoston, Massachusetts, United StatesRecruiting
Research SiteSt Louis, Missouri, United StatesRecruiting
Research SiteNew York, New York, United StatesRecruiting
Research SiteNew York, New York, United StatesRecruiting
Research SitePortland, Oregon, United StatesRecruiting
Research SitePhiladelphia, Pennsylvania, United StatesRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06218914