Condition: Insulin Sensitivity · Sponsor: Pennington Biomedical Research Center
In humans, insulin is secreted in pulses from the pancreatic beta-cells, and these oscillations help to maintain fasting plasma glucose levels within a narrow normal range. Given the fluctuations in insulin concentrations, oscillations enhance precision of control. The hyperinsulinemic euglycemic clamp test (clamp) involves a continuous infusion of insulin and is the gold standard for measuring insulin sensitivity. In this study, insulin sensitivity measured using the standard clamp will be compared with a clamp in which the same total amount of insulin as the standard clamp is infused every five minutes instead of continuously.
This description comes directly from the study's public registry record.
Candida J Rebello, Ph.D. · 225-763-3159 · Candida.Rebello@pbrc.edu
Frank L Greenway, MD · 225-763-2578 · Frank.Greenway@pbrc.edu
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| Pennington Biomedical Research Center | Baton Rouge, Louisiana, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06216665