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Study identifier: NCT06216158 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma

Condition: Multiple Myeloma  ·  Sponsor: University of Heidelberg Medical Center

PhasePhase 3
Planned participants411
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare a maintenance therapy consisting of iberdomide and isatuximab with an iberdomide-only regimen. The trial is the subsequent maintenance therapy to GMMG-HD8/DSMM XIX trial for patients with newly-diagnosed multiple myeloma. Patients with newly-diagnosed multiple myeloma who underwent a similar quadruplet induction/consolidation therapy regimen followed by at least one ASCT can also be recruited. The main question it aims to answer is: • Will the addition of isatuximab lead to decreased amounts of measurable myeloma cells in the bone marrow after two years?

This description comes directly from the study's public registry record.

Talk to the study team

Hartmut Goldschmidt, Prof.  ·  +49 6221 568198  ·  s.gmmg@med.uni-heidelberg.de

Always discuss trial participation with your own doctor first.

Locations (69)

Universitätsklinikum Krems an der DonauKrems, AustriaRecruiting
Ordensklinikum Linz ElisabethinenLinz, AustriaRecruiting
Landeskrankenhaus Salzburg, Universitätsklinik für Innere Medizin IIISalzburg, AustriaRecruiting
Klinik Ottakring WienVienna, AustriaRecruiting
Klinikum Wels-Grieskirchen GmbHWels, AustriaRecruiting
Uniklinik RWTH Aachen, Klinik für Hämatologie, Onkologie, Hämostaseologie und StammzelltransplantationAachen, GermanyRecruiting
UniversitätsklinikumAugsburg, GermanyRecruiting
Helios Klinikum Bad SaarowBad Saarow, GermanyRecruiting
Charité, III. Medizinische AbteilungBerlin, GermanyRecruiting
Vivantes Klinikum Neukölln, Klinik für Hämatologie und OnkologieBerlin, GermanyRecruiting
Helios Klinikum Berlin-BuchBerlin, GermanyRecruiting
Onkologische Schwerpunktpraxis BielefeldBielefeld, GermanyRecruiting

+ 57 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06216158