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Study identifier: NCT06215495 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Novel Target Delineation Scheme in High-grade Glioma Patients: a Randomized Single-blind Clinical Trial

Condition: Radiation Toxicity · MRI Simulated Positioning · High Grade Glioma  ·  Sponsor: Zhujiang Hospital

PhaseNA
Planned participants88
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The main question it aims to answer are: 1. whether the new target delineation scheme can improve Progression-free Survival 2. whether it can reduce the incidence of radiation complications in high-grade glioma patients. Participants in trial group will be performed radiotherapy of new target delineation method after the completion of the operation within 4-6 weeks., while participants in the control group be performed radiotherapy of EORTC(European organisation for research and treatment of cancer) target delineation method.Temozolomide 75 mg / ( m² · d ) will be given to both groups of patients during radiotherapy. After radiotherapy, its dose changes to 150 \~ 200 mg / ( m² · d ) for 5 days and stopped for 23 days as a cycle. There are 6 cycles in total.

This description comes directly from the study's public registry record.

Talk to the study team

Yujing Tan, Doctor  ·  +8613560347303  ·  tanyujing-1981@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

southern medical university affiliated Zhujiang HospitalGuangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06215495