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Study identifier: NCT06213649 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Parasitic Ulcer Treatment Trial

Condition: Acanthamoeba Keratitis  ·  Sponsor: Jeremy Keenan, MD, MPH

PhasePhase 3
Planned participants232
Who can joinAll sexes, 8 Years to no upper limit
Healthy volunteersNo

About this study

The Parasitic Ulcer Treatment Trial (PUTT) is a multi-center, parallel-group, randomized clinical trial. The purpose of this study is to determine whether including topical corticosteroids in a regimen for acanthamoeba keratitis (AK) will improve vision. Patients presenting to all enrollment centers with evidence of acanthamoeba keratitis will be eligible for the trial if there is evidence of ocular inflammation after 4 weeks of anti-amoebic therapy. Those who agree to participate will be randomized to one of two treatment groups: * Group 1: Topical corticosteroid * Group 2: Topical placebo

This description comes directly from the study's public registry record.

Talk to the study team

Jeremy Keenan, MD, MPH  ·  415-476-6323  ·  jeremy.keenan@ucsf.edu

Krisi Aromin  ·  krisianne.aromin@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (17)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting
University of Colorado AnschutzAurora, Colorado, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
University of Illinois, ChicagoChicago, Illinois, United StatesRecruiting
University of IowaIowa City, Iowa, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Columbia UniversityNew York, New York, United StatesRecruiting
Oregon Health and Science UniversityPortland, Oregon, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06213649