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Study identifier: NCT06213324 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neural Circuit Effects of Ketamine in Depression

Condition: Major Depressive Disorder  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhasePhase 4
Planned participants120
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and depression symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Sibilla Masieri  ·  sibilla.masieri@mssm.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06213324