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Study identifier: NCT06207734 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Discontinuation of CDK4/6 Inhibitors in Patients With Metastatic HR Positive, HER2 Negative Breast Cancer

Condition: Breast Cancer  ·  Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

PhasePhase 2
Planned participants120
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a low-intervention, randomized, non-comparative, open-label, multicenter, prospective, phase II trial investigating discontinuation of CDK4/6 inhibitors in patients with metastatic HR positive, HER2 negative breast cancer with durable disease control.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Decker, Prof.  ·  +49 751 366197  ·  Thomas.Decker@onkonet.eu

Regina Eickhoff, Dr.  ·  +49 69 / 5899 787  ·  eickhoff.regina@ikf-khnw.de

Always discuss trial participation with your own doctor first.

Locations (13)

Charité BerlinBerlin, GermanyRecruiting
Hämatologische Onkologische Praxis im MedicumBremen, GermanyRecruiting
St. Johannes Hospital DortmundDortmund, GermanyActive Not Recruiting
Praxis und TagesklinikFriedrichshafen, GermanyActive Not Recruiting
Hausärztliche und Onkologische GemeinschaftspraxisGerlingen, GermanyRecruiting
Onkologische GP GüterslohGütersloh, GermanyActive Not Recruiting
Hämatologisch-Onkologische Praxis AltonaHamburg, GermanyRecruiting
Universitätsmedizin der Johannes Gutenberg-Universität MainzMainz, GermanyRecruiting
MVZ für Hämatologie und Onkologie der MVZ Mülheim GmbHMülheim, GermanyRecruiting
MVZ für Hämatologie und OnkologieRavensburg, GermanyRecruiting
Krankenhaus Barmherzige Brüder RegensburgRegensburg, GermanyRecruiting
Onkologisch-Gastroenterologische Schwerpunktpraxis Innere Medizin GbRSingen, GermanyRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06207734