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Study identifier: NCT06207591 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Investigation on the Cortical Communication System

Condition: Locked-in Syndrome · Neuromuscular Diseases · Brainstem Stroke  ·  Sponsor: UMC Utrecht

PhaseNA
Planned participants2
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to demonstrate communication through a brain implant in people in locked-in state, i.e. people with severe paralysis and communication problems. The main questions it aims to answer are efficient and stable control of Brain-Computer interface (BCI) functions for communication with attempted hand movements and operation of a keyword-based speech BCI. Participants will be implanted with four electrode grids, with in total 128 electrodes, on the surface of the brain and a connector on the skull. Participation includes visits of researchers for recording and training at home, 2-3 times per week for one year. Extension of participation after one year is possible. If successful, the participant will be able to use the BCI at home independently, without the presence of a researcher.

This description comes directly from the study's public registry record.

Talk to the study team

Mariska J Vansteensel, PhD  ·  +31887555121  ·  neuroprothese@umcutrecht.nl

Erik J Aarnoutse, PhD  ·  +31887555123  ·  e.j.aarnoutse@umcutrecht.nl

Always discuss trial participation with your own doctor first.

Locations (1)

University Medical CenterUtrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06207591