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Study identifier: NCT06207123 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

Condition: Acute Leukemia · Lymphoblastic Leukemia · Lymphoblastic Lymphoma  ·  Sponsor: University of Chicago

PhasePhase 1/Phase 2
Planned participants15
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to learn more about LP-118 (an experimental drug) and its side effects and decide on acceptable doses. The purpose of this study is to determine if LP-118 can be given safely with another medicine called ponatinib, that is FDA-approved for the treatment of acute lymphoblastic leukemia.

This description comes directly from the study's public registry record.

Talk to the study team

Caner Saygin, MD  ·  773-834-8982  ·  caner.saygin@bsd.uchicago.edu

Wendy Stock, MD  ·  773-834-8982  ·  wstock@bsd.uchicago.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of Chicago Medicine Comprehensive Cancer CenterChicago, Illinois, United StatesRecruiting
University of Rochester Medical Center, Wilmot Cancer CenterRochester, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06207123