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Study identifier: NCT06206850 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neo-Bio-ADAURA: a Phase II Study to Evaluate Mechanisms of Resistance to Neoadjuvant Osimertinib

Condition: Non-squamous NSCLC  ·  Sponsor: Jair Bar, M.D., Ph.D.

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a single-arm phase II study of neoadjuvant osimertinib as monotherapy for the treatment of patients with resectable stage II-III non-small cell lung cancer (NSCLC) harboring an epidermal growth factor receptor (EGFR) sensitizing mutation (L858R or deletion in exon 19 \[Ex19del\]).

This description comes directly from the study's public registry record.

Talk to the study team

Sheba medical center  ·  +972546288901  ·  Jair.Bar@sheba.health.gov.il

Always discuss trial participation with your own doctor first.

Locations (2)

Sheba Medical CenterRamat Gan, Israel, IsraelRecruiting
Sheba Medical Center, Jusidman Cancer CenterRamat Gan, Israel, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT06206850