Condition: Pancreatic Cancer · Sponsor: University of California, San Diego
This is a phase I study of an agonistic CD40 antibody (mitazalimab) injected intratumorally at the time of surgical IRE in patients with locally advanced pancreatic cancer. Intratumoral delivery has potential to be more effective than systemic (intravenous) delivery while decreasing the systemic side effects of immunotherapy. We hypothesize that local delivery of mitazalimab at the time of IRE in patients with locally advanced pancreatic cancer will be safe, augment the immune effects of IRE, and decrease the risk of recurrence.
This description comes directly from the study's public registry record.
Shakeela Dad · 858-822-5376 · sdad@health.ucsd.edu
Always discuss trial participation with your own doctor first.
| UCSD Moores Cancer Center | La Jolla, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06205849