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Study identifier: NCT06205485 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Condition: Rectal Cancer  ·  Sponsor: Canadian Cancer Trials Group

PhasePhase 3
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being done to answer the following questions: Is the chance of rectal cancer responding the same if chemotherapy alone is given before limited surgery compared to chemotherapy and radiation therapy given together before limited surgery? If radiation therapy is not given, is quality of life better?

This description comes directly from the study's public registry record.

Talk to the study team

Chris O'Callaghan  ·  613-533-6430  ·  cocallaghan@ctg.queensu.ca

Always discuss trial participation with your own doctor first.

Locations (113)

Cancer Center at Saint Joseph'sPhoenix, Arizona, United StatesRecruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, California, United StatesRecruiting
Los Angeles General Medical CenterLos Angeles, California, United StatesRecruiting
USC / Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, California, United StatesRecruiting
Mission Hope Medical Oncology - Santa MariaSanta Maria, California, United StatesRecruiting
Beebe South Coastal Health CampusMillville, Delaware, United StatesRecruiting
Helen F Graham Cancer CenterNewark, Delaware, United StatesRecruiting
Medical Oncology Hematology Consultants PANewark, Delaware, United StatesRecruiting
Beebe Health CampusRehoboth Beach, Delaware, United StatesRecruiting
Orlando Health Cancer InstituteOrlando, Florida, United StatesSuspended
Emory University Hospital MidtownAtlanta, Georgia, United StatesRecruiting

+ 101 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06205485