Condition: Hepatocellular Carcinoma · Narrow Margin · Radiotherapy · Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences
This is a single-arm prospective phase II clinical trial to investigate the efficacy and safety of adjuvant simultaneouslyintegrated boost radiotherapy following narrow-margin(\<1cm) hepatectomy in patients with HCC. Eligibility patients will receive IMRT or VMAT to high risk area of tumor bed and tumor bed. The prescription dose to 95% GTVtb boost was planned at 55-60Gy, with PTV 45-50Gy, in 23-25 fractions, mainly depending on the dose constraints of OARs. The primary endpoint is the 3-year OS, the secondary endpoints are disease-free survival, patterns of failure, toxic events and local control rate.
This description comes directly from the study's public registry record.
Bo Chen, MD · 00861324000876 · chenboo@outlook.com
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| Bo Chen | Beijing, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06205472