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Study identifier: NCT06195384 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Anti-cancer Neoantigen mRNA Vaccine to Treat Solid Tumors

Condition: Solid Tumor, Adult  ·  Sponsor: Second Affiliated Hospital of Guangzhou Medical University

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The WES and RAN-seq will be performed to identify and verify neoantigens and appropriate mRNA sequences will be verified, manufactured and protected for vaccine production by multiple in vitro and in vivo studies. Clinical studies will be performed to test anti-cancer function of the mRNA vaccine for immunotherapy of human cancer patients. In this phase I study, the safety, tolerance, and preliminary efficacy of the mRNA vaccine immunotherapy on human cancers will firstly be evaluated.

This description comes directly from the study's public registry record.

Talk to the study team

Zhenfeng Zhang, MD, PhD  ·  0086-020-39195965  ·  zhangzhf@gzhmu.edu.cn

Bingjia He, MD  ·  +862039195965  ·  464677938@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06195384