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Study identifier: NCT06195267 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)

Condition: Aortic Dissection · Systemic Inflammatory Response Syndrome · Cardiovascular Diseases (CVD)  ·  Sponsor: Nanjing Medical University

PhaseNA
Planned participants500
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with cardiovascular diseases. Therefore, the prevention of SIRS and MODS is of great clinical value, and immunomodulatory therapy with sivelestat may be beneficial. This study was designed to test the hypothesis that the administration of sivelestat during the acute phase of cardiovascular diseases will result in a reduced incidence of SIRS and MODS.

This description comes directly from the study's public registry record.

Talk to the study team

Hong Liu, MD  ·  +8618801281613  ·  dr.hongliu@foxmail.com

Sheng Zhao, MD  ·  02568303105  ·  zhaosheng0824@163.com

Always discuss trial participation with your own doctor first.

Locations (2)

Beijing Anzhen HospitalBeijing, ChinaRecruiting
The First Affiliated Hospital of Nanjing Medical University and Jiang ye-fanNanjing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06195267