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Study identifier: NCT06193928 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)

Condition: Alagille Syndrome · Progressive Familial Intrahepatic Cholestasis  ·  Sponsor: Mirum Pharmaceuticals, Inc.

PhaseN/A
Planned participants70
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The objective of this 5-year, prospective, observational cohort study is to evaluate the long-term safety and clinical outcomes of patients with Alagille syndrome (ALGS) or Progressive familial intrahepatic cholestasis (PFIC) treated with Livmarli.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Mirum  ·  +16506674085  ·  Clinical Trials <clinicaltrials@mirumpharma.com>;

Always discuss trial participation with your own doctor first.

Locations (8)

Children's Hospital Los Angeles CHLALos Angeles, California, United StatesRecruiting
Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics and the Digestive Health Institute, Children's Hospital of Colorado and University of ColoradoAurora, Colorado, United StatesRecruiting
Children's Healthcare of Atlanta - Emory University School of MedicineAtlanta, Georgia, United StatesRecruiting
Children's Mercy Kansas City, Department of Gastroenterology, Section of HepatologyKansas City, Missouri, United StatesRecruiting
Oregon Health and Science University, Division of Pediatric Gastroenterology, Department of PediatricsPortland, Oregon, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
Children Hospital of PittsburghPittsburgh, Pennsylvania, United StatesRecruiting
University of Utah, Division of Pediatric Gastroenterology, Hepatology and NutritionSalt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06193928