Condition: Cervical Intraepithelial Neoplasia · Invasive Cervical Cancer · Sponsor: Lindsay Ferguson, MD
Normally, p53 helps prevent tumors from forming in the body. Early studies have shown that Fenofibrate, a cholesterol-lowering drug, can restore normal function to p53 and can change the metabolism of HPV-positive tumors in a way that stops the growth of tumors. The purpose of this study is to understand how Fenofibrate can be used to treat HPV-positive cervical cancers and cervical dysplasia. Researchers will examine collected tissue samples and investigate various genes and proteins to see whether Fenofibrate has an effect on HPV-positive cervical cancers and cervical dysplasia.
This description comes directly from the study's public registry record.
Lindsay A Ferguson, MD · 216-844-3954 · lindsay.ferguson@uhhospitals.org
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| University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center | Cleveland, Ohio, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06191133