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Study identifier: NCT06190886 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors

Condition: Advanced Cancer · Solid Tumor · Metastatic Cancer  ·  Sponsor: Proviva Therapeutics, Inc.

PhasePhase 1
Planned participants26
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the safety and tolerability of escalating doses of PTX-912 in patients with locally advanced or metastatic solid tumors. To evaluate the PK and immunogenicity profile of PTX-912. To evaluate the preliminary anti-tumor activity of PTX-912. Participants will be treated with PTX-912 via iv infusion, every 2 weeks until progression of disease, unacceptable toxicity, or 12 months of total study therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Project Manager  ·  425-233-1480  ·  ze.zhang@provivatx.com

Always discuss trial participation with your own doctor first.

Locations (3)

City of Hope National Medical CenterDuarte, California, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Nebraska Cancer Specialists (NCS)Omaha, Nebraska, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06190886