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Study identifier: NCT06190626 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Longitudinal Prospective Natural History Study of Retinopathy in Zellweger Spectrum Disorder

Condition: Zellweger Spectrum Disorder  ·  Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

PhaseN/A
Planned participants30
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to define the course of the retinal degeneration in a ZSD patient cohort. The objective of this study is to gather information so the investigators can: 1. define the course of the retinal degeneration in a ZSD patient cohort with retinal degeneration 2. define what tests best monitor the progression of the retinal degeneration 3. generate prognostic information about vision loss in ZSD. At each yearly visit, the participants will answer a functional vision questionnaire, have a physical evaluation, blood test, and participate in a variety of vision tests. The investigators will also collect pertinent medical history. Participants will travel to study site. The study will provide financial support for board and travel.

This description comes directly from the study's public registry record.

Talk to the study team

Nancy E Braverman, MD, MS  ·  514-934-1934  ·  nancy.braverman@mcgill.ca

Frederique Arnaud, BScN  ·  514-934-1934  ·  frederique.arnaud@muhc.mcgill.ca

Always discuss trial participation with your own doctor first.

Locations (3)

University of Rochester Medical Center/Flaum Eye InstituteRochester, New York, United StatesRecruiting
Eye Institute of AlbertaEdmonton, Alberta, CanadaRecruiting
Research Institute-McGill University Health CenterMontreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06190626