Condition: Cerebral Palsy · Hip Dysplasia · Pain, Postoperative · Sponsor: University of California, Los Angeles
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly. This is especially true in patients with cerebral palsy (CP), who often have concomitant developmental delay, intellectual disability and verbal limitations. Current literature indicates pain as a common experience for children with CP but has been understudied in this population. Moreover, inadequate post-operative pain control can result in negative physiologic and psychological complications and lead to poor surgical outcomes. Currently, perioperative pain management following orthopaedic procedures in pediatric patients follows traditional protocols that rely on the administration of opioid medications despite their known adverse side effects including nausea, vomiting, itching, constipation, urinary retention, confusion, and respiratory depression. Epidural anesthesia is a key modality in traditional pain management for pediatric patients with CP given its proven efficacy in decreasing pain and managing spasticity. Yet, administering epidural anesthesia in this patient population poses several risks including damage to preexisting intrathecal baclofen pumps, iatrogenic infection, and technically demanding insertion given high rates of concomitant neuromuscular scoliosis. Alternatively, multimodal analgesic injections theoretically offer an efficacious adjunct to traditional pain management protocols with a …
This description comes directly from the study's public registry record.
Rachel M Thompson, MD · 213-742-1369 · rathompson@mednet.ucla.edu
Nicole J Hung, MD · 310-592-5180 · nhung@mednet.ucla.edu
Always discuss trial participation with your own doctor first.
| Orthopaedic Institute for Children | Los Angeles, California, United States | Recruiting |
| Ronald Reagan UCLA Medical Center | Los Angeles, California, United States | Recruiting |
| UCLA Medical Center, Santa Monica | Santa Monica, California, United States | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago, Illinois, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06189781