● Recruiting

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

Condition: Myotonic Dystrophy Type 1 (DM1) · Sponsor: Vertex Pharmaceuticals Incorporated

PhasePhase 1/Phase 2

Planned participants52

Who can joinAll sexes, 18 Years to 64 Years

Healthy volunteersNo

About this study

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of VX-670 at different single and multiple doses in participants with DM1.

This description comes directly from the study's public registry record.

Talk to the study team

Medical Information · 617-341-6777 · medicalinfo@vrtx.com

Always discuss trial participation with your own doctor first.

Locations (26)

Stanford Neuromuscular Research	San Carlos, California, United States	Recruiting
University of Florida Clinical Research Center	Gainesville, Florida, United States	Recruiting
University of Kansas Medical Center	Fairway, Kansas, United States	Recruiting
Boston Children's Hospital	Boston, Massachusetts, United States	Recruiting
Washington University School of Medicine / St. Louis Children's Hospital	St Louis, Missouri, United States	Recruiting
Wake Forest Baptist Health	Winston-Salem, North Carolina, United States	Recruiting
University of Pennsylvania	Philadelphia, Pennsylvania, United States	Recruiting
Virginia Commonwealth University (Sanger Hall)	Richmond, Virginia, United States	Recruiting
Wesley Research Institute	Auchenflower, Australia	Recruiting
Neuroscience Clinical Trials Unit, Alfred Brain	Melbourne, Australia	Recruiting
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg	Leuven, Belgium	Recruiting
Hopital de Chicoutimi	Chicoutimi, Canada	Recruiting

+ 14 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06185764