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Study identifier: NCT06185673 Synced from ClinicalTrials.gov · July 29, 2026
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A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Condition: Oculopharyngeal Muscular Dystrophy  ·  Sponsor: Benitec Biopharma, Inc.

PhasePhase 1/Phase 2
Planned participants30
Who can joinAll sexes, N/A to 65 Years
Healthy volunteersNo

About this study

Subjects who have enrolled in the oculopharyngeal muscular dystrophy (OPMD) natural history study (Study BNTC-OPMD-NH-001) and have completed at least 6 months of follow up in Study BNTC-OPMD-NH-001 may be eligible to participate in this study, where all subjects will be treated with a single dose of BB-301. BB-301 will be injected directly into the middle pharyngeal constrictor muscle and the inferior pharyngeal constrictor muscle of the throat through the use of an open surgical procedure conducted under general anesthesia. The primary objectives of the study are to evaluate the safety of BB-301, to identify the best dose of BB-301 to administer to patients, and to characterize how well BB-301 works to improve the symptoms of dysphagia in patients with OPMD.

This description comes directly from the study's public registry record.

Talk to the study team

Jerel A. Banks, M.D., Ph.D.  ·  (510)-780-0634  ·  jbanks@benitec.com

Sophie Mukadam  ·  smukadam@benitec.com

Always discuss trial participation with your own doctor first.

Locations (1)

NYU Langone HealthNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06185673