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Study identifier: NCT06184503 Synced from ClinicalTrials.gov · July 29, 2026
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Analysis of Velmanase Alfa (Lamzede®)'s Effects in the Body of Children With Alpha-Mannosidosis Under the Age 3

Condition: Alpha-Mannosidosis  ·  Sponsor: Chiesi Farmaceutici S.p.A.

PhaseN/A
Planned participants5
Who can joinAll sexes, N/A to 3 Years
Healthy volunteersNo

About this study

The goal of this observational study is to learn the effects of the drug velmanase alfa (Lamzede®) in the bodies of children under the age of 3 with Alpha-Mannosidosis. The main questions it aims to answer are: * study the effect of velmanase alfa on a marker of the disease called GlcNAc(Man)2 after one year of therapy * explore how the child's body reacts to velmanase alfa during the therapy The parents or legal guardians of participants will be asked to provide the results of analyses performed in the routine clinical setting related to the participant's general health and the administration of velmanase alfa. Additional data will be extracted from other observational sponsored studies/registries, compassionate use programs, investigator-initiated studies (IIS), and published case reports (presented in the literature) if existing.

This description comes directly from the study's public registry record.

Talk to the study team

Chiesi Clinical trials  ·  +39.0521 2791  ·  clinicaltrials_info@chiesi.com

Always discuss trial participation with your own doctor first.

Locations (2)

Nicklaus Children's HospitalMiami, Florida, United StatesRecruiting
Greenwood Genetic CenterGreenwood, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06184503