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Study identifier: NCT06184321 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Condition: Hematopoietic and Lymphoid Cell Neoplasm · Malignant Solid Neoplasm  ·  Sponsor: M.D. Anderson Cancer Center

PhaseEARLY_Phase 1
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study investigates whether alteplase can help to improve pleural fluid drainage and dyspnea (breathlessness) in patients with non-draining malignant pleural effusion. Alteplase helps dissolve blood clots and is used to treat heart attacks, strokes, and clots in the lungs. Alteplase may help to control symptoms of breathlessness.

This description comes directly from the study's public registry record.

Talk to the study team

Horiana Grosu, M D  ·  713-792-6238  ·  hbgrosu@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06184321