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Study identifier: NCT06184009 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Treatment of Newly Diagnosed High Risk Pediatric Acute Lymphoblastic Leukemia

Condition: Pediatric Acute Lymphoblastic Leukemia  ·  Sponsor: Jae Wook Lee

PhasePhase 2
Planned participants370
Who can joinAll sexes, 1 Year to 19 Years
Healthy volunteersNo

About this study

* Clinical and genetic factors consistent with High risk : Induction → Consolidation 1. BM MRD \&lt; 0.01% : IM #1 → DI #1 → IM #2 → Maintenance 2. BM MRD ≥ 0.01% : IM #1 → DI #1 → IM #2 → DI #2 → Maintenance 3. BM MRD ≥ 0.01% after Consolidation <!-- --> 1. T cell ALL : Change to very high risk regimen 2. Pre-B ALL : IM #1 → Intensification 1. BM MRD \&lt; 0.01% after IM #1 : DI #1 → IM #2 → DI #2 → Maintenance 2. BM MRD ≥ 0.01% after IM #1 : Change to Very high risk regimen * Difference in the number of \&#39;interim maintenance(IM)\&#39; and \&#39;delayed intensification(DI)\&#39; is important for chemotherapies based on MRD.

This description comes directly from the study's public registry record.

Talk to the study team

Jae Wook Lee, Ph.D  ·  82-2-2258-6192  ·  dashwood@catholic.ac.kr

Always discuss trial participation with your own doctor first.

Locations (7)

Seoul National University HospitalSeoul, Seoul, South KoreaRecruiting
Samsung Medical CenterSeoul, Seoul, South KoreaRecruiting
Korea University Anam HospitalSeoul, South KoreaNot Yet Recruiting
Severance HospitalSeoul, South KoreaRecruiting
Asan Medical CenterSeoul, South KoreaRecruiting
Seoul saint Mary's HospitalSeoul, South KoreaRecruiting
Pusan National University Yangsan HospitalYangsan, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT06184009