Condition: Anesthesia · Sponsor: Technical University of Munich
This observational study aims to investigate healthy cortical and subcortical neural processes involved in generating intrinsic alpha oscillations during induction of general anesthesia with propofol. To do this, the investigators have designed a simultaneous electroencephalogram (EEG)- MRI (functional MRI and Spectroscopy) experiment with a visual stimulation paradigm that addresses the subject's specific intrinsic alpha rhythm during anesthesia and wakefulness. The main question it aims to answer is: could the investigators address the alpha oscillation system of the healthy brain with external stimulation during anesthesia? This experiment could lead to a better understanding of the mechanisms underlying the generation of alpha oscillations. It could open new doors to diagnostic and treatment options for diseases where alpha oscillations, such as post-operative delirium, seem to be affected.
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| Klinikum rechts der Isar - Klinik für Anästhesiologie und Intensivmedizin | Munich, Bavaria, Germany | Recruiting |
| Technische Universität München | München, München (Stadt), Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06179719