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Study identifier: NCT06179680 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

White Matter Hyperintensities in Amnestic Mild Cognitive Impairment or Alzheimer's Disease

Condition: Mild Cognitive Impairment · Alzheimer Disease  ·  Sponsor: IRCCS Policlinico S. Donato

PhaseN/A
Planned participants142
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersYes

About this study

This study focuses on assessing and measuring white matter hyperintensities in individuals with amnestic mild cognitive impairment (aMCI) or Alzheimer's disease. Objective: The primary objective of the study is to quantify the extent and distribution of white matter hyperintensities in the brains of individuals diagnosed with amnestic mild cognitive impairment or Alzheimer's disease. White matter hyperintensities are areas of increased signal intensity observed on brain magnetic resonance imaging (MRI) scans, often associated with various cognitive disorders. Importance: Understanding the presence and severity of white matter hyperintensities in individuals with aMCI or Alzheimer's disease is crucial for several reasons. These abnormalities may serve as potential biomarkers, aiding in the early diagnosis and prognosis of cognitive disorders. Additionally, quantifying white matter hyperintensities could contribute to a better comprehension of the underlying neuropathological processes associated with these conditions. Methods: The study employs advanced imaging techniques, likely including MRI, to capture and analyze white matter hyperintensities in the brains of participants with amnestic mild cognitive impairment or Alzheimer's disease. The quantification process involves precise measurement and mapping of these hyperintense regions. Participants: The study involves individuals diagnosed with amnestic mild cognitive impairment or Alzheimer's disease. Participants wil…

This description comes directly from the study's public registry record.

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Locations (1)

IRCCS Policlinico San DonatoSan Donato Milanese, Milano, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06179680