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Study identifier: NCT06179160 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Condition: Solid Tumors  ·  Sponsor: Incyte Corporation

PhasePhase 1
Planned participants710
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.

This description comes directly from the study's public registry record.

Talk to the study team

Incyte Corporation Call Center (US)  ·  1.855.463.3463  ·  medinfo@incyte.com

Incyte Corporation Call Center (ex-US)  ·  +800 00027423  ·  eumedinfo@incyte.com

Always discuss trial participation with your own doctor first.

Locations (34)

Mayo Clinic HospitalPhoenix, Arizona, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
UCLA Healthcare Hematology-OncologySanta Monica, California, United StatesRecruiting
Sarah Cannon Research Institue At HealthoneDenver, Colorado, United StatesRecruiting
Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Sidney Kimmel Comprehensive Cancer Center At Johns HopkinsBaltimore, Maryland, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting
Weill Cornell MedicineNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Jefferson University HospitalsPhiladelphia, Pennsylvania, United StatesRecruiting
Scri Oncology PartnersNashville, Tennessee, United StatesRecruiting

+ 22 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06179160