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Study identifier: NCT06173518 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)

Condition: Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia · Relapsed or Refractory B Cell Non-Hodgkin Lymphoma  ·  Sponsor: Autolus Limited

PhasePhase 1
Planned participants30
Who can joinAll sexes, 0 Years to 18 Years
Healthy volunteersNo

About this study

This is a Phase 1b/2 study to evaluate the safety and efficacy of autologous T cells engineered with a chimeric antigen receptor (CAR) targeting cluster of differentiation (CD)19 in pediatric patients with relapsed or refractory (r/r) B cell acute lymphoblastic leukemia (B ALL) and r/r B cell Non-Hodgkin lymphoma (B NHL).

This description comes directly from the study's public registry record.

Talk to the study team

Autolus Ltd  ·  +44 (0) 203 911 4385  ·  clinicaltrials@autolus.com

Always discuss trial participation with your own doctor first.

Locations (8)

Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
Methodist Children's HospitalSan Antonio, Texas, United StatesRecruiting
Primary Children's HospitalSalt Lake City, Utah, United StatesRecruiting
Hospital Vall d'HebronBarcelona, SpainRecruiting
Hospital Nino JesusMadrid, SpainRecruiting
Great Ormond Street Hospital for Children NHS Foundation TrustLondon, United KingdomRecruiting
Royal Manchester Children's HospitalManchester, United KingdomRecruiting
Great North Children's HospitalNewcastle upon Tyne, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06173518