Condition: Advanced Prostate Adenocarcinoma · Stage III Prostate Cancer AJCC v8 · Stage IV Prostate Cancer AJCC v8 · Sponsor: University of California, Davis
This phase II trial compares the effects, good and/or bad of abiraterone and prednisone or darolutamide alone in treating patients with prostate cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Androgens (male hormones) can cause the growth of prostate tumor cells. Abiraterone acetate lowers the amount of androgens made by the body. This may help stop the growth of prostate tumor cells that need androgen to grow. Darolutamide blocks the use of androgens by the tumor cells. Prednisone is used to lessen inflammation and lower the body's immune response. Researchers want to compare the side effects of standard of care (SOC) abiraterone and prednisone or darolutamide alone in treating patients with advanced prostate cancer.
This description comes directly from the study's public registry record.
OCR Referral Team · 916-382-6970 · OCRReferral@health.ucdavis.edu
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| University of California Davis Comprehensive Cancer Center | Sacramento, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06173362