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Study identifier: NCT06173349 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PLZ4-Coated Paclitaxel-Loaded Micelles for the Treatment of Patients With Recurrent or Refractory Non-Muscle Invasive Bladder Cancer

Condition: Recurrent Non-Muscle Invasive Bladder Carcinoma · Stage 0a Bladder Cancer AJCC v8 · Stage 0is Bladder Cancer AJCC v8  ·  Sponsor: University of California, Davis

PhasePhase 1
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase I trial tests the safety, tolerability and effectiveness of PLZ4-coated paclitacel-loaded micelles (PPM) in treating patients with non-muscle invasive bladder cancer that has come back after a period of improvement (recurrent) or that does not respond to treatment (refractory). PPM is a bladder cancer-specific nanoparticle that can specifically target and deliver treatment to the tumor cells in the bladder. PPM contains paclitaxel, which is a drug that kills tumor cells or keeps them from growing.

This description comes directly from the study's public registry record.

Talk to the study team

Office of Clinical Research  ·  916-382-6970  ·  OCRReferral@health.ucdavis.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California Davis Comprehensive Cancer CenterSacramento, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06173349