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Study identifier: NCT06170736 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease

Condition: Haemorrhoids · Internal Haemorrhoids · Grade II/III Haemorrhoids  ·  Sponsor: Centre Hospitalier Departemental Vendee

PhaseNA
Planned participants168
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Surgical treatment of grade II/III internal haemorrhoidal disease is indicated in the case of medical and/or instrumental treatment failure. Minimal invasive alternatives to haemorrhoidectomy have been introduced in the last decades to treat grade II/III haemorrhoids. Doppler-Guided haemorrhoidal artery ligation (DGHAL) represents a good therapeutic option in this condition with good short and mid-term outcomes but postoperative recurrence rates up to 35% at 5 years. Recently, a technique of radiofrequency ablation (RFA) has been introduced with promising outcomes. A recent systematic review reported a significant improvement of preoperative symptoms and a recurrence rate \< 5%. To date, there is no study comparing DGHAL to RFA in the treatment of grade II/III haemorrhoids. The aim of this study is to demonstrate the non-inferiority in terms of failure rate of haemorrhoidal radiofrequency ablation compared to Doppler-guided haemorrhoidal artery ligation, associated with mucopexy, in the treatment of grade II and III haemorrhoidal disease

This description comes directly from the study's public registry record.

Talk to the study team

Agnès DORION  ·  251446380  ·  agnes.dorion@ght85.fr

Always discuss trial participation with your own doctor first.

Locations (18)

Centre Hospitalier UniversitaireAmiens, FranceRecruiting
Centre Hospitalier UniversitaireAngers, FranceRecruiting
Maison de Santé BagatelleBordeaux, FranceRecruiting
Centre Hospitalier PrivéBrest, FranceRecruiting
Clinique du val d'OuestÉcully, FranceRecruiting
Centre Hospitalier Départemental de VendéeLa Roche-sur-Yon, FranceRecruiting
Hôpital de la LouvièreLille, FranceRecruiting
CHU LimogesLimoges, FranceRecruiting
Clinique de la SauvegardeLyon, FranceRecruiting
Centre Hospitalier UniversitaireNantes, FranceRecruiting
Clinique Jules VerneNantes, FranceRecruiting
Hôpital Saint JosephParis, FranceRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06170736