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Study identifier: NCT06164704 Synced from ClinicalTrials.gov · July 27, 2026
● Completed

A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps

Condition: Chronic Rhinosinusitis With Nasal Polyps  ·  Sponsor: Upstream Bio Inc.

PhasePhase 2
Planned participants81
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

The primary purpose of this study is to assess the effect of verekitug (UPB-101) on the endoscopically determined size and extend of nasal polyps in participants with chronic rhinosinusitis with nasal polyps (CRSwNP) and to assess the safety and tolerability of verekitug (UPB-101) compared to placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (41)

Sensa Health LA (Sensa Health Clinical Research)Los Angeles, California, United States
NewportNativeMD, Inc.Newport Beach, California, United States
DaVinci, Research LLCRoseville, California, United States
Senta ClinicSan Diego, California, United States
University of MissouriColumbus, Colorado, United States
Western States Clinical Research, Inc.Wheat Ridge, Colorado, United States
Alfa Medical ResearchHollywood, Florida, United States
Novaceut Clinical ResearchMiami, Florida, United States
Well Pharma Medical Research Corp.Miami, Florida, United States
IMIC Inc.Miami, Florida, United States
University of South FloridaTampa, Florida, United States
Treasure Valley Medical ResearchBoise, Idaho, United States

+ 29 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06164704