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Study identifier: NCT06160635 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

D-SOLVE Cohorts (Cohort a and B)

Condition: HDV · HDV Infection · Chronic Liver Disease  ·  Sponsor: Hannover Medical School

PhaseN/A
Planned participants750
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Hepatitis D is by far the most severe form of chronic viral hepatitis, frequently leading to liver failure, hepatocellular carcinoma and death. Hepatitis D is caused by coinfection Hepatitis D is caused by co-infection with hepatitis B virus (HBV) and hepatitis D virus (HDV). This multicenter cohort should enable a comprehensive and unbiased biomarker screening of well-defined HDV-infected patients, followed by mechanistic studies to determine the functional role of distinct molecules. Patient surveillance strategies and antiviral treatment approaches could be personalized which should reduce clinical and social disease burden, improve quality of life and save direct and indirect costs caused by HDV infection.

This description comes directly from the study's public registry record.

Talk to the study team

Petra Dörge  ·  +495115326057  ·  doerge.petra@mh-hannover.de

Julia Kahlhöfer  ·  kahlhoefer.julia@mh-hannover.de

Always discuss trial participation with your own doctor first.

Locations (4)

Hannover Medical School, Department of Gastroenterology, Hepatology, Infectious Disease and EndocrinologyHanover, GermanyRecruiting
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (University of Milan)Milan, ItalyNot Yet Recruiting
Institutul de Boli Infectioase "Prof. Dr. Matei Bals"Bucharest, RomaniaRecruiting
Karolinska University Hospital and Karolinska InstitutetStockholm, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT06160635