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Study identifier: NCT06160284 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Condition: Opioid Use Disorder  ·  Sponsor: Yale University

PhasePhase 1
Planned participants12
Who can joinAll sexes, 25 Years to 55 Years
Healthy volunteersNo

About this study

This study will examine the synaptotrophic effects of psilocybin among medically healthy, detoxified OUD subjects. Eligible OUD participants will undergo pre- and post- psilocybin administration PET scans with the \[11C\]-UCB-J radiotracer while inpatient.

This description comes directly from the study's public registry record.

Talk to the study team

Gustavo Angarita, MD, MHS  ·  (203) 974-7536  ·  gustavo.angarita@yale.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Yale UniversityNew Haven, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06160284