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Study identifier: NCT06159166 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

Condition: NF1 · Cutaneous Neurofibroma · Monotherapy  ·  Sponsor: Johns Hopkins University

PhasePhase 1/Phase 2
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1/2a, open-label, non-randomized, multi-dose study of mirdametinib monotherapy in adults with NF1 and cNF. In both Phases of the study, participation in the study will comprise three periods: screening, treatment and post-study safety follow-up to be performed at the NF1 and cNF specialty center: Johns Hopkins University.

This description comes directly from the study's public registry record.

Talk to the study team

Carlos Romo, MD  ·  (410) 955-6827  ·  cromo1@jhmi.edu

Joshua Roberts  ·  4109558837  ·  jrobe112@jh.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06159166